Effect of Corticosteroids and Neuropeptides on the Expression of Defensins in 2 Bovine Tracheal Epithelial Cells
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چکیده
1 Effect of Corticosteroids and Neuropeptides on the Expression of Defensins in 2 Bovine Tracheal Epithelial Cells 3 4 5 6 7 8 9 Running Title: Dexamethasone inhibits defensin expression 10 11 12 Gordon B. Mitchell*, Muthafar H. Al-Haddawi, Mary Ellen Clark, Jennifer D. 13 Beveridge, Jeff L. Caswell 14 15 Department of Pathobiology, Ontario Veterinary College, University of Guelph 16 Guelph, ON, Canada, N1G 2W1 17 18 19 * Corresponding author: Gordon B. Mitchell, Department of Pathobiology, 20 University of Guelph, Guelph, ON, Canada N1G 2W1 21 TEL: 519-824-4120 FAX: 519-824-5930 22 email: [email protected] 23 AC CE PT ED Copyright © 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Infect. Immun. doi:10.1128/IAI.00686-06 IAI Accepts, published online ahead of print on 11 December 2006
منابع مشابه
Effect of corticosteroids and neuropeptides on the expression of defensins in bovine tracheal epithelial cells.
Susceptibility to bacterial pneumonia in cattle is enhanced by stressors such as transportation, weaning, and commingling, which trigger a physiologic stress response resulting in elevated levels of endogenous corticosteroids and catecholamines. To determine the effect of neuroendocrine mediators on the expression of innate defense peptides in the lung, bovine tracheal epithelial cells were exp...
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